Inspire Pharmaceuticals

Diacoll-S

Introduction

Diacoll-S is a Collagen – Gentamicin in the form sponge / containing collagen and Gentamicin sulphate. The collagen Gentamicin implant is composed of highly purified Type-l collagen which acts as a vehicle for the antimicrobial gentamicin. The collagen is derived from specifically controlled and certified animals and is highly purified to avoid any antiginicity. Gentamicin sulphate is a wide spectrum antibiotic that provides highly effective topical treatment in primary and secondary bacterial infections of the skin. Diacoll-STM is produced using the latest triple helix collagen technique to provide an optimum degree of flexibility and rigidity combined with the most predictable resorptive process.

Indications

Diacoll-S can be applied in a number of surgeries to reduce the risk of Surgical Site infections.

  • Cardiothorasic
  • Orthopedic
  • GI/Abdominal
  • Vascular/ Plastic
  • Diabetic Foot Ulcer (Osteomyelitis)

How supplied:

Diacoll-s Implant is Supplied in the following sizes in a gamma sterilized pouch

Available Sizes

  •  5X5cms
  • 10X 10 cms
  • 5X 20cms

Mechanism Of Action

Diacoll-s comprises of a collagen sponge incorporated with Gentamicin sulphate. When applied on the wound the collagen acts as a vehicle for the antimicrobial gentamicin. Collagen is absorbed slowly by the tissue in 6 to 10 days after is application. The Diacoll-S kills bacteria that may be antibiotic-resistant at lower doses. It maintains a high concentration of the drug at the target site, while avoiding the risk of systemic toxicity and associated side effects. It comes prepacked and sterile and is intended for single use only.

Precautions & Comments

  • Wounds may appear larger during first several days of treatment due to reduction of edema
  • An increase in drainage may be seen in the first several days of treatment
  • Treatment oft the underlying conditions (enous or arterial flow, external pressure as well as nutritional support should proceed concurrently with the use of Diacoll-S
  • Avoid patient hypersensitive to Collagen, Gentamicin.
  • A transient buning sensation may be experienced by a small percentage of patients.

Application of Diacoll-S Implant on the First Day.

A) Prepare the wound bed

1) AJ Change and dispose of the old dressing in a sate, caretul and appropriate manner.

B Accomplish appropriate wound debriment

1) Take the appropriate size of the Diacoll-S Cut open the sterile pouch.
2) Cut the Diacol-Saccording to the shape of the wOund and apply it to the wound surtace.
3) When applied to the wound surface it tends to adapt extremely well to the bone /tissue walls.

C) Wound care dressing

1) The area may be covered with Gauze dressing it desired.

Directions For Use

  • In all cases standard establishesterilele surgical procedures must be observed
  • Dial-S should be cut to the desired size to ideally extend 2-3mm beyond the
    edge of the details).
  • The sheet once wet with blood tends to adapt extremely well to the bone/ tissue walls.